FDI-6 ( FDI-6 | FDI 6 | FDI6 | NCGC00099374 )

产品货号. M17474 CAS No. 313380-27-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

FDI-6
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

FDI-6 是一种有效的选择性 FOXM1 抑制剂，可阻断 DNA 结合。 FDI-6 与 FOXM1 蛋白结合并特异性下调 FOXM1 激活基因。
产品描述

FDI-6 is an inhibitor of FOXM1 that block DNA binding. It act by specifically downregulating FOXM1-activated genes with FOXM1 occupancy confirmed by ChIP-PCR.
体外实验

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体内实验

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同义词

FDI-6 | FDI 6 | FDI6 | NCGC00099374
通路

Endocrinology/Hormones
靶点

Opioid Receptor
受体

FOXM1
研究领域

——
适应症

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CAS Number

313380-27-7
分子量

437.43
分子式

C19H11F4N3OS2
纯度

>98% (HPLC)
溶解度

DMSO : ≥ 50 mg/mL; 114.30 mM
SMILES

C1=CSC(=C1)C2=NC3=C(C(=C2)C(F)(F)F)C(=C(S3)C(=O)NC4=CC=C(C=C4)F)N
化学全称

3-Amino-N-(4-fluorophenyl)-6-thiophen-2-yl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide

1. Gormally MV., et al. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nat Commun. 2014 Nov 12;5:5165.

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