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K-Ras(G12C) Inhibitor 6
CAS No. 2060530-16-5
K-Ras(G12C) Inhibitor 6 ( K-Ras(G12C) Inhibitor 6 | MDK30165 )
产品货号. M17423 CAS No. 2060530-16-5
K-Ras(G12C) 抑制剂 6 是 K-Ras(G12C) 突变体的不可逆变构抑制剂，在体外以 10 μM 浓度使用 24 小时时，会导致蛋白质 100% 发生修饰。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥611 | 有现货 |
|
| 5MG | ￥1093 | 有现货 |
|
| 10MG | ￥1853 | 有现货 |
|
| 25MG | ￥3125 | 有现货 |
|
| 50MG | ￥4213 | 有现货 |
|
| 100MG | ￥4887 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥1093 | 有现货 |
|
生物学信息
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产品名称K-Ras(G12C) Inhibitor 6
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述K-Ras(G12C) 抑制剂 6 是 K-Ras(G12C) 突变体的不可逆变构抑制剂，在体外以 10 μM 浓度使用 24 小时时，会导致蛋白质 100% 发生修饰。
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产品描述MDK30165, also known as K-Ras(G12C) Inhibitor 6. It has no formal code name. For the convenience of communication, we name it as MDK30165. It has CAS#2060530-16-5, in which the last 5 digit is used for its code name. K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.
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体外实验——
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体内实验——
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同义词K-Ras(G12C) Inhibitor 6 | MDK30165
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通路Others
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靶点Other Targets
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受体K-Ras
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研究领域Cancer
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适应症——
化学信息
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CAS Number2060530-16-5
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分子量405.33
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分子式C17H22Cl2N2O3S
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纯度>98% (HPLC)
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溶解度——
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SMILESClc1ccc(OCC(=O)N2CCC(NC(=O)CCCS)CC2)c(Cl)c1
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化学全称N-(1-(2-(2,4-dichlorophenoxy)acetyl)piperidin-4-yl)-4-mercaptobutanamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Hunter JC, Gurbani D, Ficarro SB, Carrasco MA, Lim SM, Choi HG, Xie T, Marto JA, Chen Z, Gray NS, Westover KD. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8895-900.
产品手册
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