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VUF10460
CAS No. 1028327-66-3
VUF10460 ( —— )
产品货号. M17121 CAS No. 1028327-66-3
VUF10460 是一种非咪唑组胺 H4 受体激动剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥425 | 有现货 |
|
| 10MG | ￥661 | 有现货 |
|
| 25MG | ￥1097 | 有现货 |
|
| 50MG | ￥1628 | 有现货 |
|
| 100MG | ￥2295 | 有现货 |
|
| 200MG | ￥3267 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥345 | 有现货 |
|
生物学信息
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产品名称VUF10460
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述VUF10460 是一种非咪唑组胺 H4 受体激动剂。
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产品描述VUF10460 is a non-imidazole histamine H4 receptor agonist.
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体外实验UF10460 binds to rat H3 and H4 receptor with pKi values of 5.75, and 7.46, respectively. VUF10460 displays approximately a 50-fold selectivity for the rat H4 receptor over the H3 receptor.
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体内实验HCl-induced rat gastric lesions is significantly enhanced by the H4 receptor agonists VUF10460. This effect is not modified by H4 receptor antagonist JNJ7777120.
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同义词——
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通路Others
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靶点Other Targets
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受体H4 receptor
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number1028327-66-3
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分子量269.35
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分子式C15H19N5
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 36 mg/mL 133.66 mM
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SMILESCN1CCN(CC1)c1cc(c2ccccc2)nc(N)n1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Coruzzi G, et al. Selective histamine H3 and H4 receptor agonists exert opposite effects against the gastric lesions induced by HCl in the rat stomach. Eur J Pharmacol. 2011 Nov 1;669(1-3):121-7.
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