Synephrine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

交感α-肾上腺素能激动剂，具有类似去氧肾上腺素的作用。

Sympathetic alpha-adrenergic agonist with actions like PHENYLEPHRINE. It is used as a vasoconstrictor in circulatory failure, asthma, nasal congestion, and glaucoma.(In Vivo):Synephrine (1 mg/kg; oral gavage; for 8 days; PVL and BDL rats) significantly ameliorates the hyperdynamic state in both PVL and BDL rats. The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index are significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance are enhanced by treatment of Synephrine.

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Animal Model:Portal vein ligation (PVL) or bile duct ligation (BDL) rats Dosage:1 mg/kg per 12 hours Administration:Oral gavage; for 8 days Result:The portal venous pressure in PVL and BDL rats, portal tributary blood flow and cardiac index were significantly reduced, while mean arterial pressure and systemic as well as portal territory vascular resistance were enhanced.

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Endocrinology/Hormones

Adrenergic Receptor

Adrenergic Receptor

Other Indications

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94-07-5

167.21

C9H13NO2

>98% (HPLC)

Ethanol: 2 mg/mL warmed (11.96 mM); DMSO: 33 mg/mL warmed (197.35 mM)

CNCC(O)C1=CC=C(O)C=C1

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(-20℃)

With Ice Pack

≥ 2 years