Liranaftate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Liranaftate 是一种角鲨烯环氧酶抑制剂，具有抗真菌活性。

Liranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities.(In Vitro):Liranaftate showed excellent fungistatic activity against the conidia of T. rubrum. For each of these agents, the MIC after 14 days of contact was 0.009 g/ml. The liranaftate-induced decrease in the MCC occurred from 9 days onwards; MCC at 14 days was 0.039 g/ml . In time-kill studies, liranaftate showed the greatest decrease to a below detection limit in viable counts of T rubrum. The degree of killing of the strain by amorolfine was not greater than that seen by liranaftate, and little reduction of the viable counts by luliconazole and ketoconazole was observed irrespective of concentrations of the agents .

Liranaftate showed excellent fungistatic activity against the conidia of T. rubrum. For each of these agents, the MIC after 14 days of contact was 0.009 g/ml. The liranaftate-induced decrease in the MCC occurred from 9 days onwards; MCC at 14 days was 0.039 g/ml . In time-kill studies, liranaftate showed the greatest decrease to a below detection limit in viable counts of T rubrum. The degree of killing of the strain by amorolfine was not greater than that seen by liranaftate, and little reduction of the viable counts by luliconazole and ketoconazole was observed irrespective of concentrations of the agents .

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Liranaftate | M-732 | Piritetrate

Microbiology/Virology

Antifungal

squalene epoxidase

Infection

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88678-31-3

328.43

C18H20N2O2S

>98% (HPLC)

DMSO: >5mM

O=C(OC1=CC=C2CCCCC2=C1)N(SC)C3=NC(OC)=CC=C3

O-(5,6,7,8,-Tetrahydro-2-naphthyl) 6-methoxy-N-methylthio-2-pyridinecarbamate

(-20℃)

With Ice Pack

≥ 2 years