Chloroxylenol ( —— )

产品货号. M16385 CAS No. 88-04-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Chloroxylenol
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

氯二甲酚（4-氯-3,5-二甲基苯酚）是一种广谱抗菌化合物，用于控制细菌、藻类、真菌和病毒。
产品描述

Chloroxylenol (4-chloro-3,5-dimethylphenol) is a broad spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus. It is used in hospitals and households for disinfection and sanitation.
体外实验

RT-PCR Cell Line:HCT116 and SW480 CRC cells Concentration:62.5-250 μM Incubation Time:24 h Result:Decreased mRNA level Axin2, Survivin and LGR5, which indicates the antagonistic effect of Chloroxylenol on the Wnt/β-catenin signaling.
体内实验

Animal Model:MC38 cell xenograft modelDosage:5 mg/kg Administration:i.p., on days 0, 2, 4, 6, 8 and 10 Result:Reduced umor volume and weight.Reduced tumor cell density (H&E).Inhibited the expression of cancer stemness marker LGR5 in the tumor tissue, as well as the expression levels of LGR5 and SOX2.
同义词

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通路

Others
靶点

Other Targets
受体

Others
研究领域

Infection
适应症

——

1. Xu L, Wang J. Environ Eng Sci. 2013 Jun;30(6):294-30

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