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Dehydroepiandrosterone acetate

CAS No. 853-23-6

Dehydroepiandrosterone acetate ( —— )

产品货号. M16196 CAS No. 853-23-6

醋酸脱氢表雄酮是肾上腺皮质产生的主要 C19 类固醇。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥300 有现货
1G 获取报价 有现货
1 mL x 10 mM in DMSO ¥397 有现货

生物学信息

  • 产品名称
    Dehydroepiandrosterone acetate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    醋酸脱氢表雄酮是肾上腺皮质产生的主要 C19 类固醇。
  • 产品描述
    Dehydroepiandrosterone acetate is a major C19 steroid produced by the adrenal cortex. (In Vivo):Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.
  • 体外实验
    ——
  • 体内实验
    Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.
  • 同义词
    ——
  • 通路
    Endocrinology/Hormones
  • 靶点
    Androgen Receptor (AR)
  • 受体
    Androgen Receptor
  • 研究领域
    Endocrinology
  • 适应症
    ——

化学信息

  • CAS Number
    853-23-6
  • 分子量
    330.46
  • 分子式
    C21H30O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 10 mM
  • SMILES
    CC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CCC4=O)C)C
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Stárka L, et al. J Steroid Biochem Mol Biol. 2015 Jan;145:254-60.
产品手册
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