The peptide region containing residues 390-404 in Activated Protein C (APC) is essential for anticoagulant activity and is available for interaction with antibodies or with other proteins, such as the macromolecular substrates Factors Va or VIIIa. APC regulates blood coagulation by proteolytic inactivation of the blood coagulation cofactors Va and VIIIa.

Adrenomedullin (26-52) (human)

促肾上腺皮质激素 (ACTH) (4-10) 是一种有效的黑皮质素 (MC4R) 受体激动剂。在人类中，促肾上腺皮质激素 (ACTH) (4-10) 鼻内应用后进入脑液室，导致全身减少连续治疗6周后脂肪减少。