Bambuterol hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

一种长效 β-肾上腺素受体激动剂 (LABA)，用于治疗哮喘。

A long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; also is a prodrug of terbutaline.Asthma Approved(In Vitro):Bambuterol ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.

Bambuterol ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.

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KWD-2183

GPCR/G Protein

Adrenergic Receptor

AChR|β-adrenergicreceptor

Inflammation/Immunology

Asthma

81732-46-9

403.9009

C18H30ClN3O5

>98% (HPLC)

DMSO: < 7.6 mg/mL

CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O.Cl

Carbamic acid, N,N-dimethyl-, 3-[[(dimethylamino)carbonyl]oxy]-5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]phenyl ester, hydrochloride (1:1)

(-20℃)

With Ice Pack

≥ 2 years