• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Sulfathiazole

CAS No. 72-14-0

Sulfathiazole ( HSDB4380 | HSDB-4380 | HSDB 4380 | Sulfathiazole | Planomide | Poliseptil )

产品货号. M15758 CAS No. 72-14-0

磺胺噻唑是一种有机硫化合物,已被用作短效磺胺化合物。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥147 有现货
1G ¥222 有现货
1 mL x 10 mM in DMSO ¥170 有现货

生物学信息

  • 产品名称
    Sulfathiazole
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    磺胺噻唑是一种有机硫化合物,已被用作短效磺胺化合物。
  • 产品描述
    Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.(In Vitro):Sulfathiazole (20 μg/L) starts to be degraded between day 31 and day 38 in one of the two batch reactors containing different wastewater matrices. Sulfathiazole is degraded at a substantially faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3). Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level]. Sulfathiazole sorption to inorganic sorbents exhibits pronounced pH dependence consistent with sorbate speciation and sorbent charge properties. Sulfathiazole cations are most important for sorption to clay minerals, followed by neutral species.
  • 体外实验
    Sulfathiazole (20 μg/L) starts to be degraded between day 31 and day 38 in one of the two batch reactors containing different wastewater matrices. Sulfathiazole is degraded at a substantially faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3). Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level]. Sulfathiazole sorption to inorganic sorbents exhibits pronounced pH dependence consistent with sorbate speciation and sorbent charge properties. Sulfathiazole cations are most important for sorption to clay minerals, followed by neutral species.
  • 体内实验
    ——
  • 同义词
    HSDB4380 | HSDB-4380 | HSDB 4380 | Sulfathiazole | Planomide | Poliseptil
  • 通路
    Autophagy
  • 靶点
    Autophagy
  • 受体
    DHPS| DHPS
  • 研究领域
    Infection
  • 适应症
    ——

化学信息

  • CAS Number
    72-14-0
  • 分子量
    255.32
  • 分子式
    C9H9N3O2S2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 51 mg/mL (199.74 mM)
  • SMILES
    O=S(NC1=NC=CS1)(C2=CC=C(N)C=C2)=O
  • 化学全称
    4-amino-N-(thiazol-2-yl)benzenesulfonamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Nichols BP, Guay GG. Antimicrob Agents ChemOthers. 1989 Dec;33(12):2042-8.
产品手册
关联产品
  • SJFα

    SJFα 是一种 13 个原子长度 linker 的基于von Hippel-Lindau 配体的 PROTAC。SJFα 降解 p38α,DC50 为 7.16 nM,但降解 p38δ 效果较差 (DC50=299 nM),且在浓度高达 2.5 μM 时也不会降解其他 p38 亚型 (β 和 γ)。

  • MPP+ iodide

    MPP+ 碘化物是神经毒素 MPTP 的代谢产物,通过选择性破坏黑质中的多巴胺能神经元,在动物模型中引起帕金森病 (PD) 症状。

  • GSK4112

    一种有效的选择性小分子 Rev-erbα 激动剂,生化测定中 EC50 为 0.4 uM。