Fluocinolone acetonide

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Fluocinolone Acetonide 是一种与胞质糖皮质激素受体结合的皮质类固醇。

Fluocinolone Acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor.

Cell Proliferation Assay Cell Line:DCPs Concentration:0.1 μmol/L, 1 μmol/L, 10 μmol/L, 20 μmol/L, 40 μmol/L, 60 μmol/L, 100 μmol/L Incubation Time:24 h Result:Significantly promoted the growth rate of DPCs of a low concentration.Western Blot Analysis Cell Line:DCPs Concentration:1 μmol/L, 10 μmol/L Incubation Time:7 days Result:Showed higher expressions of DSPP and Wnt4 protein than negative control.

Animal Model:PTX-induced peripheral neuropathy model Dosage:500 μg/kg Administration:Intraperitoneal injection (i.p.)Result:Prevented a marked reduction in intraepidermal nerve fibers density in the plantar surface of the hind paws.

NSC 92339

Others

Other Targets

Others

Inflammation/Immunology

——

67-73-2

452.49

C24H30F2O6

>98% (HPLC)

Ethanol: 12 mg/mL (26.51 mM); DMSO: 90 mg/mL (198.89 mM)

O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@]4(C)[C@]5(C(CO)=O)OC(C)(C)O[C@]5([H])C[C@@]4([H])[C@]3([H])C[C@H](F)C2=C1

(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

(-20℃)

With Ice Pack

≥ 2 years