Nanchangmycin ( Nanchangmycin A )

产品货号. M15472 CAS No. 65101-87-3

一种从南昌链霉菌 NS3226 中分离出来的聚醚离子载体抗生素，具有抗菌和抗病毒特性。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
5MG	￥1017	有现货
10MG	￥1644	有现货
25MG	￥3236	有现货
500MG	获取报价	有现货
1G	获取报价	有现货
1 mL x 10 mM in DMSO	￥1596	有现货

产品询价大包装询价加入购物车

生物学信息

产品名称

Nanchangmycin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

一种从南昌链霉菌 NS3226 中分离出来的聚醚离子载体抗生素，具有抗菌和抗病毒特性。
产品描述

A polyether ionophore antibiotic isolated from Streptomyces nanchangensis NS3226 that shows antibacterial and antiviral properties; A potent inhibitor of Zika virus entry, also is active against other medically relevant viruses, including West Nile, dengue, and chikungunya viruses.
体外实验

Nanchangmycin can be used as a growth promotant in poultry and to cure coccidiosis in chickens. Nanchangmycin is active against drug resistant strains of malaria. Nanchangmycin as a potent inhibitor of Zika virus (ZIKV) entry across all cell types tested including physiologically relevant primary cells. Nanchangmycin potently reduces infection of all three strains of ZIKV across all three cell types. The IC50s for infection are between 0.1 and 0.4 μM while Nanchangmycin has low toxicity in these ranges. In addition, DENV is inhibited by Nanchangmycin across cell types.
体内实验

——
同义词

Nanchangmycin A
通路

GPCR/G Protein
靶点

Antibacterial
受体

Others
研究领域

Other Indications
适应症

——

化学信息

CAS Number

65101-87-3
分子量

889.0956
分子式

C47H77NaO14
纯度

>98% (HPLC)
溶解度

DMSO: ≥ 26 mg/mL
SMILES

C[C@H]([C@@H](O1)[C@H](C)[C@@H](O)C[C@@]21CC[C@@](C)([C@@H](C[C@H](OC3O[C@H](C)[C@@H](OC)CC3)[C@H]4C)O[C@]54[C@@H](C)C[C@H]([C@H]6O[C@](CO)(O)[C@H](C)C[C@@H]6C)O5)O2)/C=C(C)/C([C@H](C)C[C@H](C)C([O-])=O)=O.[Na+]
化学全称

6-Nonenoic acid, 8-[(2S,2'R,4'S,5R,5'S,7R,7'R,8R,9S,9'S,10'R)-9-hydroxy-2,4',8,10'-tetramethyl-2'-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9'-[[(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy][2,7'-bi-1,

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Liu T, et al. Chem Biol. 2008 May;15(5):449-58. 2. Liu T, et al. Chem Biol. 2006 Sep;13(9):945-55. 3. Rausch K, et al. Cell Rep. 2017 Jan 17;18(3):804-815.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册