Meglumine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

葡甲胺是一种源自山梨糖醇的氨基糖。

Meglumine is an amino sugar derived from sorbitol. It is often used as an excipient in pharmaceuticals and in conjunction with iodinated compounds in contrast media such as diatrizoate meglumine and iodipamide meglumine.

Western Blot Analysis Cell Line:C2C12 mouse myoblasts Concentration:0, 10, 30, 100, 300 mM or 200 mM Incubation Time:60 min or 0, 10, 30, 60, 120 min Result:Increased the levels of SNARK protein in a dose-dependent manner after 60 min and reached a plateau at 30 minutes.

Animal Model:Sprague-Dawley ratDosage:25 or 50 mM Administration:p.o., dissolve in water Result:Reduced the isoprostane levels in rats.Animal Model:K6/ODC transgenic mice Dosage:37.5 mM Administration:p.o., dissolve in water Result:Reduced the number of skin tumors and inhibited tumor growth.Animal Model:KK.Cg-Ay/J mice Dosage:18 mM Administration:p.o., in drinking water Result:Performed better in a glucose tolerance test.Decreased their average fasting levels of glucose and triglyceride levels in both the liver and blood serum.

1-Deoxy-1-(methylamino)-D-glucitol | Iosulamide | N-Methyl-D-glucamine

Others

Other Targets

Others

Other Indications

——

6284-40-8

195.21

C7H17NO5

>98% (HPLC)

Water: 39 mg/mL (199.78 mM); DMSO: 39 mg/mL (199.78 mM)

O[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)CNC

(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol

(-20℃)

With Ice Pack

≥ 2 years