Zoxazolamine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Zoxazolamine 被广泛用于活性分子测试，可作为啮齿动物细胞色素 P-450 活性变化的方便指标。

Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood.

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Zoxazolamine is widely used for a pharmacologic test that serves as a convenient indicator of changes in cytochrome P-450 activity in rodents. The time-averaged serum clearance determined from tested concentrations data is 7.22±1.01 mL/min/kg for Zoxazolamine. Infusion of Zoxazolamine to righting reflex (LRR) at three different rates shows increasing Zoxazolamine concentration in serum and brain at the onset of the effect with increasing infusion rates. When the Zoxazolamine infusion is continued for 5 min beyond the onset of LRR, the concentrations of Zoxazolamine in the cerebrospinal fluid (CSF) at the offset of LRR are essentially identical to the onset concentrations.

2-Amino-5-chlorobenzoxazole | Contrazole | NSC 24995

Others

Other Targets

Others

Other Indications

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61-80-3

168.58

C7H5ClN2O

>98% (HPLC)

Ethanol: 34 mg/mL (201.68 mM); DMSO: 34 mg/mL (201.68 mM)

c1cc2c(cc1Cl)nc(o2)N

2-Benzoxazolamine, 5-chloro- (9CI)

(-20℃)

With Ice Pack

≥ 2 years