Closantel sodium ( —— )

产品货号. M15316 CAS No. 61438-64-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Closantel sodium
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Closantel sodium 是有效的抗寄生虫活性的卤化水杨酰苯胺。Closantel sodium 是一种有效且高度特异性的盘尾丝虫几丁质酶 (OvCHT1) 抑制剂，IC50 为 1.6 μM，Ki 为 468 nM。Closantel sodium 抑制了食蟹曲霉 L3 至 L4 的蜕皮。
产品描述

A veterinary anthelmintic with known proton ionophore activities; is identified as a potent and specific inhibitor of filarial chitinases; also shows to be an allosteric inhibitor of SPAK and OSR1.Parasite Infection Approved(In Vitro):Closantel sodium, a known anthelmintic drug, is highly specific forfilarial family chitinases compared to those fromprotozoans and the human chitinase, human chitotriosidase.
体外实验

Closantel sodium, a known anthelmintic drug, is highly specific forfilarial family chitinases compared to those fromprotozoans and the human chitinase, human chitotriosidase.
体内实验

——
同义词

——
通路

Microbiology/Virology
靶点

Parasite
受体

Others
研究领域

Infection
适应症

Parasite Infection

CAS Number

61438-64-0
分子量

685.0555
分子式

C22H13Cl2I2N2NaO2
纯度

>98% (HPLC)
溶解度

10 mM in DMSO
SMILES

CC1=CC(=C(C=C1NC(=O)C2=C(C(=CC(=C2)I)I)O)Cl)C(C#N)C3=CC=C(C=C3)Cl.[Na]
化学全称

Benzamide, N-[5-chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodo-, sodium salt (1:1)

1. AlAmri MA, et al. ChemMedChem. 2017 May 9;12(9):639-645. 2. Gloeckner C, et al. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3424-9.

计算器

产品手册

关联产品

Antimalarial agent 3...

Antimalarial agent 30 (compound 11) 是一种抗疟剂，抑制伯氏疟原虫肝期寄生虫的 EC500 为 5.2 μM。
Febantel

非班太尔是一种驱虫药。用于兽医用狗、猫、牛、绵羊、山羊、猪和家禽对抗蛔虫和绦虫。
Emodepside

PF1022A的半合成衍生物，新型环缩酚肽驱虫药，对多种胃肠道线虫有效。