Sulfamethazine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

磺胺二甲嗪是一种磺胺类抗菌药。

Sulfamethazine is a sulfonamide antibacterial.(In Vivo):Sulfamethazine (80 mg/kg; intravenous injection; healthy female pigs) treatment significantly reduces α, β and AUC0->∞, significantly increases t1/2α, Vd and CIB, and upon a single intramuscular administration of 80 mg/kg of Sulfamethazine the absolute bioavailability in pigs is 1.01.

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Sulfamethazine (80 mg/kg; intravenous injection; healthy female pigs) treatment significantly reduces α, β and AUC0->∞, significantly increases t1/2α, Vd and CIB, and upon a single intramuscular administration of 80 mg/kg of Sulfamethazine the absolute bioavailability in pigs is 1.01. Animal Model:19 healthy female pigs (6-week-old, 4.5-6.2 kg) Dosage:80 mg/kg Administration:Intravenous injection (Pharmacokinetic study)Result:The half-life in distribution phase is 0.23 h and half-lifes in eliminations phase is 9.8 h. α, β and the AUC0->∞ were significantly decreased and t1/2α, Vd and CIB were significantly increased, and the absolute bioavailability in pigs is 1.01.

NSC 67457 | NSC 683529 | Sulfadimethyldiazine | Sulfadimidine

Others

Other Targets

Others

Infection

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57-68-1

278.34

C12H14N4O2S

>98% (HPLC)

DMSO: 56 mg/mL (201.2 mM)

CC1=C(S(=O)(C2=CC=C(N)C=C2)=O)C(C)=NC(N)=N1

5-((4-aminophenyl)sulfonyl)-4,6-dimethylpyrimidin-2-amine

(-20℃)

With Ice Pack

≥ 2 years