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L-(-)-α-Methyldopa

CAS No. 555-30-6

L-(-)-α-Methyldopa ( Methyldopa | MK-351 | NSC 169916 )

产品货号. M15017 CAS No. 555-30-6

甲基多巴是一种α-肾上腺素能激动剂(对α2-肾上腺素能受体有选择性)精神活性化合物,用作交感神经药或抗高血压药。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥129 有现货
100MG ¥165 有现货
200MG ¥223 有现货
500MG ¥354 有现货
1G ¥509 有现货
1 mL x 10 mM in DMSO ¥167 有现货

生物学信息

  • 产品名称
    L-(-)-α-Methyldopa
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    甲基多巴是一种α-肾上腺素能激动剂(对α2-肾上腺素能受体有选择性)精神活性化合物,用作交感神经药或抗高血压药。
  • 产品描述
    Methyldopa is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.(In Vivo):Methyldopa hydrate (L-(-)-α-Methyldopa hydrate; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment.
  • 体外实验
    ——
  • 体内实验
    Methyldopa (L-(-)-α-Methyldopa; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment. Animal Model:60-day-old male rats Dosage:200 mg/kg Administration:I.p.Result: Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration.
  • 同义词
    Methyldopa | MK-351 | NSC 169916
  • 通路
    GPCR/G Protein
  • 靶点
    Dopamine Receptor
  • 受体
    DOPA decarboxylase
  • 研究领域
    Cardiovascular Disease
  • 适应症
    ——

化学信息

  • CAS Number
    555-30-6
  • 分子量
    211.21
  • 分子式
    C10H13NO4
  • 纯度
    >98% (HPLC)
  • 溶解度
    Ethanol: <1 mg/mL (<1 mM); Water: <1 mg/mL (<1 mM); DMSO: <1 mg/mL (<1 mM)
  • SMILES
    O=C(O)[C@@](C)(N)CC1=CC=C(O)C(O)=C1
  • 化学全称
    (S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Head GA. Ann N Y Acad Sci. 1999 Jun 21;881:279-86.
产品手册
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