Rapamycin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

一种大环内酯化合物，通过抑制 mTOR 具有有效的免疫抑制和抗增殖特性 (IC50=0.1 nM)。

A macrolide compound that has potent immunosuppressive and antiproliferative properties by inhibiting mTOR (IC50=0.1 nM).Other Indication Approved(In Vitro):Rapamycin (GMP) (1 nM; 2-3 weeks) induces in vitro differentiation of human embryonic stem cell (hESCs) into mineralized osteoblasts.Rapamycin (GMP) (1 nM; 2-3 weeks) enhances the osteoblastic differentiation of human embryoid bodies (hEBs).Rapamycin (GMP) (20 nM; 4 h) serum-dependently promotes vascular smooth muscle cells (VSMCs) differentiation.Rapamycin (GMP) induces osteoblastic differentiation in rat osteoblast-like osteosarcoma cells.

Rapamycin (GMP) (1 nM; 2-3 weeks) induces in vitro differentiation of human embryonic stem cell (hESCs) into mineralized osteoblasts.Rapamycin (GMP) (1 nM; 2-3 weeks) enhances the osteoblastic differentiation of human embryoid bodies (hEBs).Rapamycin (GMP) (20 nM; 4 h) serum-dependently promotes vascular smooth muscle cells (VSMCs) differentiation.Rapamycin (GMP) induces osteoblastic differentiation in rat osteoblast-like osteosarcoma cells.

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Sirolimus

PI3K/Akt/mTOR signaling

mTOR

mTOR

Other Indications

Other Disease

53123-88-9

914.1719

C51H79NO13

>98% (HPLC)

DMSO: ≥ 28 mg/mL

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Rapamycin

(-20℃)

With Ice Pack

≥ 2 years