Vitamin D2

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

维生素D2对糖精钠促进膀胱肿瘤有很强的抑制作用，并能诱导白血病细胞的细胞分化。

Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.(In Vivo):At sacrifice, after 5 weeks of treatment, chickens receiving omeprazole alone or omeprazole in combination with either restricted food intake or Ergocalciferol weighed 15-25% less (P < 0.01) than chickens given vehicle or receiving reduced amount of food.Combined treatments of fasting and ergocalciferol show more deleterious effects on growth than fasting only or ergocalciferol only and induced face anomalies.

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At sacrifice, after 5 weeks of treatment, chickens receiving omeprazole alone or omeprazole in combination with either restricted food intake or Ergocalciferol weighed 15-25% less (P < 0.01) than chickens given vehicle or receiving reduced amount of food.Combined treatments of fasting and ergocalciferol show more deleterious effects on growth than fasting only or ergocalciferol only and induced face anomalies. Animal Model:83 chickens (White Leghorn), weighing 318 ± 9 g.Dosage:250,000 IU/kg Administration:S.C. once daily.Result:Induced a long-lasting hypercalcemia in rat and mice and suppresses the expression of PTH mRNA in the rat.

Calciferol | Ergocalciferol | Fortodyl | Infron | Mulsiferol | NSC 62792 | Radiostol | Uvesterol D

Cell Cycle/DNA Damage

DNA/RNA Synthesis

DNA polymerase| VD3

Metabolic Disease

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50-14-6

396.65

C28H44O

>98% (HPLC)

Ethanol: 80 mg/mL (201.68 mM); DMSO: 20 mg/mL (50.42 mM)

O[C@@H]1C/C(C(CC1)=C)=C/C=C2[C@]3([H])CC[C@H]([C@H](C)/C=C/[C@H](C)C(C)C)[C@@]3(C)CCC/2

(S,Z)-3-(2-((1R,3aS,7aR,E)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexan-1-ol

(-20℃)

With Ice Pack

≥ 2 years