Ethyl ferulate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

阿魏酸乙酯是从当归、川芎中提取的。

Ethyl ferulate is extracted from angelica, Chuan Xiong.

Western Blot Analysis Cell Line:RPE cells (induced by 150 μM CoCl2 for 12 h)Concentration:40 μM Incubation Time:2 h Result:Increased Nrf-2 expression and nuclear translocation.Decreased Keap-1 expression, Aand increased HO-1 and NQO-1 expression.Reduced hypoxia-induced HIF-1α and VEGFA expression.

Animal Model:LPS (0.5 mg/kg)-induced acute lung injury mice model Dosage:15 and 30 mg/kg Administration:i.p., twice a day for 5 days Result:Reduced leukocyte infiltration.Reduced MPO activity, mRNA levels and secretion of TNF-α and IL-6.

BBR 3222 | NSC 14879

Others

Other Targets

Others

Other Indications

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4046-02-0

222.24

C12H14O4

>98% (HPLC)

DMSO: 10 mM

CCOC(=O)/C=C/C1=CC(=C(C=C1)O)OC

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(-20℃)

With Ice Pack

≥ 2 years