Trimebutine
CAS No. 39133-31-8
Trimebutine ( —— )
产品货号. M14347 CAS No. 39133-31-8
曲美布汀是一种具有抗毒蕈碱和弱μ阿片激动作用的化合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 200MG | ¥97 | 有现货 |
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| 500MG | ¥156 | 有现货 |
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| 1G | ¥223 | 有现货 |
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| 1 mL x 10 mM in DMSO | ¥120 | 有现货 |
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生物学信息
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产品名称Trimebutine
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述曲美布汀是一种具有抗毒蕈碱和弱μ阿片激动作用的化合物。
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产品描述Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects.Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.
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体外实验——
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体内实验——
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同义词——
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通路Endocrinology/Hormones
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靶点Opioid Receptor
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受体Opioid Receptor
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研究领域Metabolic Disease
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适应症——
化学信息
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CAS Number39133-31-8
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分子量387.47
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分子式C22H29NO5
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纯度>98% (HPLC)
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溶解度DMSO: 50 mg/mL (129.04 mM)
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SMILESCCC(COC(=O)C1=CC(OC)=C(OC)C(OC)=C1)(N(C)C)C1=CC=CC=C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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[D-Ser2] Leu-Enkepha...
DSLET ([D-Ser2, Leu5, Thr6]-enkephalin) 是一种高度特异性的 δ-受体激动剂。DSLET 是一种脑啡肽相关肽,可以与 δ 阿片受体选择性结合。
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[Arg14,Lys15]Nocicep...
Highly potent and selective NOP receptor agonist (EC50 = 1 nM). Displays > 875-fold selectivity over opioid receptors (IC50 values are 0.32, 280, > 10000 and 1500 for NOP, μ, δ and κ receptors respectively). Longer lasting and 30-fold more potent than nociceptin in vivo; pronociceptive and inhibits locomotor activity.
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CTOP
Potent and selective μ opioid receptor antagonist (Ki values are 0.96 and >10,000 nM for μ and δ receptors respectively). Causes behavioral effects on central administration in vivo. Also increases K+ currents in rat locus ceruleus neurons in vitro via a μ receptor independent mechanism.
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