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Pyrantel tartrate
CAS No. 33401-94-4
Pyrantel tartrate ( —— )
产品货号. M14131 CAS No. 33401-94-4
Pyrantel tartrate 是一种抗线虫噻吩；由于体壁肌肉上的兴奋性烟碱乙酰胆碱（nACh）受体的长时间激活，可以引起寄生虫的痉挛性肌肉麻痹。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥114 | 有现货 |
|
| 100MG | ￥147 | 有现货 |
|
| 500MG | ￥372 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥131 | 有现货 |
|
生物学信息
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产品名称Pyrantel tartrate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Pyrantel tartrate 是一种抗线虫噻吩；由于体壁肌肉上的兴奋性烟碱乙酰胆碱（nACh）受体的长时间激活，可以引起寄生虫的痉挛性肌肉麻痹。
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产品描述Pyrantel tartrate is an antinematodal thiophene; and can elicit spastic muscle paralysis in parasitic worms due to prolonged activation of the excitatory nicotinic acetylcholine (nACh) receptors on body wall muscle.(In Vitro):Pyrantel tartrate (10 nM-10 μM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity.(In Vivo):Pyrantel tartrate (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%.
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体外实验Pyrantel tartrate (10 nM-10 μM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity. Cell Viability AssayCell Line:A. suum Concentration:10 nM-10 μM Incubation Time:72 h Result:Inhibited A. suum with a pEC50 value of 7.24.Cell Viability Assay Cell Line:N. americanus Concentration:0-168.2 M (0-100 μg/mL)Incubation Time:72 h Result:Inhibited third-stage larvae and adult of N. americanus with IC50 values of 2.0 and 7.6 mg/mL, respectively.
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体内实验Pyrantel tartrate (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%. Animal Model:Male Syrian Golden hamsters (3-week-old; A. ceylanicum-infected).Dosage:10 mg/kg Administration:Oral administration; single.Result:Exhibited worm burden reduction and worm expulsion rates of 87.2% and 63.4%, respectively.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域Infection
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适应症——
化学信息
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CAS Number33401-94-4
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分子量356.39
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分子式C15H20N2O6S
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纯度>98% (HPLC)
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溶解度DMSO: 10 mM
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SMILESCN1CCCN=C1/C=C/C2=CC=CS2.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Pratt SE, et al. Am J Vet Res. 1981 May;42(5):871-2.
产品手册
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