Gliquidone ( Gliquidone | Glurenorm | Beglynor | Glikvidon | Glycvidon )

产品货号. M14125 CAS No. 33342-05-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Gliquidone
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Gliquidone 是磺酰脲类抗糖尿病化合物。它用于治疗2型糖尿病。
产品描述

Gliquidone is an anti-diabetic drug in the sulfonylurea class. It is used in the treatment of diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.
体外实验

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体内实验

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同义词

Gliquidone | Glurenorm | Beglynor | Glikvidon | Glycvidon
通路

Cell Cycle/DNA Damage
靶点

Potassium Channel
受体

Potassium Channel
研究领域

Endocrinology
适应症

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CAS Number

33342-05-1
分子量

527.63
分子式

C27H33N3O6S
纯度

>98% (HPLC)
溶解度

Ethanol: 6 mg/mL (11.37 mM); DMSO: 105 mg/mL (199.0 mM)
SMILES

CC1(C2=C(C=C(C=C2)OC)C(=O)N(C1=O)CCC3=CC=C(C=C3)S(=O)(=O)NC(=O)NC4CCCCC4)C
化学全称

1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea

1.Angel I, et al. Fundam Clin Pharmacol, 1991, 5(2), 107-115.

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