Isoconazole nitrate ( —— )

产品货号. M13698 CAS No. 24168-96-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Isoconazole nitrate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

硝酸异康唑 (Travogen) 是一种唑类抗真菌试剂。
产品描述

Isoconazole nitrate (Travogen) is an azole antifungal reagent.(In Vitro):Isoconazole nitrate also exerts several other effects on the fungal membrane, which are independent of inhibition of the ergosterol synthesis. Isoconazole nitrate (ISN) causes a rapid reduction of cellular adenosine triphosphate (ATP) within 10 min of in vitro exposure.Isoconazole nitrate (1, 10 μg/mL) induces a blockade of cell division in vitro by its action on synthesis and organisation of the cell membrane. Isoconazole nitrate (50, 100 μg/mL), ISN induced necrosis and death of fungal cells.
体外实验

Isoconazole nitrate also exerts several other effects on the fungal membrane, which are independent of inhibition of the ergosterol synthesis. Isoconazole nitrate (ISN) causes a rapid reduction of cellular adenosine triphosphate (ATP) within 10 min of in vitro exposure.Isoconazole nitrate (1, 10 μg/mL) induces a blockade of cell division in vitro by its action on synthesis and organisation of the cell membrane. Isoconazole nitrate (50, 100 μg/mL), ISN induced necrosis and death of fungal cells.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

Others
研究领域

Infection
适应症

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1.Veraldi S.Mycoses. 2013 May;56 Suppl 1:41-3.

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