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Cinepazide

CAS No. 23887-46-9

Cinepazide ( —— )

产品货号. M13690 CAS No. 23887-46-9

一种脑血管扩张剂,具有钙阻滞剂的作用。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
25MG ¥9858 有现货
50MG ¥12834 有现货
100MG ¥15750 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Cinepazide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    一种脑血管扩张剂,具有钙阻滞剂的作用。
  • 产品描述
    A cerebral vasodilator that acts as a calcium blocker; protect neuronal cells against OGD injury by suppressing OGD-induced oxidative stress and preserving mitochondrial functions.Ischemia Approved.
  • 体外实验
    ——
  • 体内实验
    Cinepazide (intravenous?injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects.Cinepazide (intravertebral injection; 1-10 mg/kg) increases vertebral blood flow in a dose-related manner and the effect is partially inhibited by Aminophylline (HY-B0140)?in dogs.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Other Targets
  • 研究领域
    Cardiovascular Disease
  • 适应症
    Ischemia

化学信息

  • CAS Number
    23887-46-9
  • 分子量
    417.4986
  • 分子式
    C22H31N3O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCN(CC2)CC(=O)N3CCCC3
  • 化学全称
    Piperazine, 1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-, (E)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Miwa S, et al. Jpn J Pharmacol. 1986 May;41(1):109-15. 2. Zhao J, et al. Neurol Sci. 2014 Jun;35(6):875-81. 3. Li Y, et al. Biol Pharm Bull. 2017 Mar 1;40(3):249-255.
产品手册
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