Eslicarbazepine Acetate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Eslicarbazepine acetate (BIA 2-093) 是一种抗癫痫活性分子，也是 β-内分泌酶 (β-Secretase) 和电压门控钠离子通道 (sodium channel) 的双抑制剂。

Eslicarbazepine acetate is an antiepileptic drug. (In Vivo):Eslicarbazepine acetate is an antiepileptic drug. It is a prodrug which is activated to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine. Eslicarbazepine acetate is a prodrug for (S)-(+)-licarbazepine, the major active metabolite of oxcarbazepine. Its mechanism of action is therefore identical to that of oxcarbazepine. Eslicarbazepine acetate may not produce as high peak levels of (S)-(+)-licarbazepine immediately after dosing as does oxcarbazepine which could theoretically improve tolerability.

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Eslicarbazepine acetate is an antiepileptic drug. It is a prodrug which is activated to eslicarbazepine (S-licarbazepine), an active metabolite of oxcarbazepine. Eslicarbazepine acetate is a prodrug for (S)-(+)-licarbazepine, the major active metabolite of oxcarbazepine. Its mechanism of action is therefore identical to that of oxcarbazepine. Eslicarbazepine acetate may not produce as high peak levels of (S)-(+)-licarbazepine immediately after dosing as does oxcarbazepine which could theoretically improve tolerability.

BIA 2-093

Others

Other Targets

Others

Neurological Disease

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236395-14-5

296.324

C17H16N2O3

>98% (HPLC)

DMSO: 59 mg/mL (199.1 mM)/Ethanol: 11 mg/mL (37.12 mM)

O=C(N1C2=CC=CC=C2C[C@H](OC(C)=O)C3=CC=CC=C31)N

(S)-10-Acetoxy- 10,11-dihydro- 5H-dibenz[b,f]azepine- 5-carboxamide

(-20℃)

With Ice Pack

≥ 2 years