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Benfotiamine

CAS No. 22457-89-2

Benfotiamine ( Benzoylthiamine monophosphate )

产品货号. M13604 CAS No. 22457-89-2

苯磷硫胺,一种脂溶性硫胺素衍生物,用于治疗糖尿病神经病变。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
25MG ¥121 有现货
50MG ¥182 有现货
100MG ¥254 有现货
200MG ¥358 有现货
500MG ¥582 有现货
1G ¥896 有现货
1 mL x 10 mM in DMSO ¥694 有现货

生物学信息

  • 产品名称
    Benfotiamine
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    苯磷硫胺,一种脂溶性硫胺素衍生物,用于治疗糖尿病神经病变。
  • 产品描述
    Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)protein kinase C (PKC) pathway)of hyperglycemic damage and prevent experimental diabetic retinopathy. Benfotiamine is a synthetic S-acyl derivative of thiamine (vitamin B1) for treating sciatica and other painful nerve conditions. More effective at increasing thiamin levels in blood and tissues than water-soluble salts like the previous vitamin B1.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    Benzoylthiamine monophosphate
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    22457-89-2
  • 分子量
    466.46
  • 分子式
    C19H23N4O6PS
  • 纯度
    >98% (HPLC)
  • 溶解度
    Soluble in DMSO
  • SMILES
    O=C(S/C(CCOP(O)(O)=O)=C(N(CC1=CN=C(C)N=C1N)C=O)/C)C2=CC=CC=C2
  • 化学全称
    (Z)-S-(2-(N-((4-amino-2-methylpyrimidin-5-yl)methyl)formamido)-5-(phosphonooxy)pent-2-en-3-yl) benzothioate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Bozic I, et al. PLoS One. 2015 Feb 19;10(2):e0118372.
产品手册
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