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Calycosin
CAS No. 20575-57-9
Calycosin ( Calycosin )
产品货号. M13198 CAS No. 20575-57-9
Calycosin (Cyclosin) 是一种具有抗氧化和抗炎活性的天然活性化合物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥610 | 有现货 |
|
| 10MG | ￥1017 | 有现货 |
|
| 25MG | ￥1665 | 有现货 |
|
| 50MG | ￥2474 | 有现货 |
|
| 100MG | ￥3420 | 有现货 |
|
| 200MG | ￥4887 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
| 1 mL x 10 mM in DMSO | ￥671 | 有现货 |
|
生物学信息
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产品名称Calycosin
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Calycosin (Cyclosin) 是一种具有抗氧化和抗炎活性的天然活性化合物。
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产品描述Calycosin (Cyclosin) is a natural active compound with anti-oxidative and anti-inflammation activity.
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体外实验Cell Proliferation Assay Cell Line:MCF-7 cells Concentration:2-32 μM Incubation Time:48 h Result:Increased the MCF-7 cell number at the doses of 2-8 μM.Inhibited the proliferation of MCF-7 cells at the doses of 32 μM.
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体内实验Animal Model:Adult Male Sprague-Dawley RatsDosage:7.5-30 mg/kg Administration:i.g. daily, 3 days Result:Improved neurological deficit and infarct volum.Reduced the content of malondialdehyde (MDA), protein carbonyl and reactive oxygen species (ROS).Increased the activities of superoxide dismutase (SOD), catalase and glutathione peroxidase (GSH-Px) in a dose-dependent manner.Inhibited the expression of 4-Hydroxy-2-nonenal (4-HNE).
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同义词Calycosin
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通路Others
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靶点Other Targets
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受体TyrosiN/Ase
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研究领域Cancer
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适应症——
化学信息
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CAS Number20575-57-9
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分子量284.26
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分子式C16H12O5
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纯度>98% (HPLC)
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溶解度Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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SMILESO=C1C(C2=CC=C(OC)C(O)=C2)=COC3=C1C=CC(O)=C3
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化学全称7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Zhou Y, et al. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. Tumour Biol. 2015 Feb 12.
2. Chen J, et al. Calycosin and genistein induce apoptosis by inactivation of HOTAIR/p-Akt signaling pathway in human breast cancer MCF-7 cells. Cell Physiol Biochem. 2015;35(2):722-8.
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