Amifostine

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Amifostine 是一种细胞保护佐剂，用于涉及 DNA 结合化疗药物的 Y 化疗和放疗。

Amifostine is a cytoprotective adjuvant used in Y chemotherapy and radiotherapy involving DNA-binding chemotherapeutic agents.

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Animal Model:Male C57BL/6 mice with myocardial I/R injury Dosage:400 mg/kg Administration:Intravenous injection; 4 hours Result:Attenuated cardiomyocyte apoptosis and reduced the production of I/R-induced ROS. Significantly reduced the expression of cleaved caspase 3 and Bax whileenhanced the expression of SOD1, SOD2 and Bcl2.Significantly increased SOD activity and reduced MDA levels.

Amifostine

Others

Other Targets

Others

Cancer

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20537-88-6

214.22

C5H15N2O3PS

>98% (HPLC)

Soluble in Water

NCCCNCCSP(O)(O)=O

2-((3-Aminopropyl)amino)-ethanethiol, dihydrogen phosphate ester (9CI)

(-20℃)

With Ice Pack

≥ 2 years