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首页- Products - Membrane Transporter/Ion Channel - Sodium Channel - Mepivacaine hydrochloride

Mepivacaine hydrochloride

CAS No. 1722-62-9

Mepivacaine hydrochloride ( —— )

产品货号. M12620 CAS No. 1722-62-9

甲哌卡因是一种用作局部麻醉剂的叔胺。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
200MG ￥129 有现货
500MG ￥178 有现货
1G ￥259 有现货
1 mL x 10 mM in DMSO ￥143 有现货
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生物学信息

  • 产品名称
    Mepivacaine hydrochloride
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    甲哌卡因是一种用作局部麻醉剂的叔胺。
  • 产品描述
    Mepivacaine is a tertiary amine used as a local anesthetic.(In Vitro):Mepivacaine hydrochloride binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action.Mepivacaine hydrochloride has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine).Mepivacaine hydrochloride displays a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displays a preference for TTXs Na(+) channels.
  • 体外实验
    Mepivacaine hydrochloride binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action.Mepivacaine hydrochloride has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine).Mepivacaine hydrochloride displays a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displays a preference for TTXs Na(+) channels.
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Membrane Transporter/Ion Channel
  • 靶点
    Sodium Channel
  • 受体
    Sodium Channel
  • 研究领域
    Neurological Disease
  • 适应症
    ——

化学信息

  • CAS Number
    1722-62-9
  • 分子量
    282.81
  • 分子式
    C15H22N2O·HCl
  • 纯度
    >98% (HPLC)
  • 溶解度
    Ethanol: 8 mg/mL (28.28 mM); Water: 57 mg/mL (201.54 mM); DMSO: 3 mg/mL (10.6 mM)
  • SMILES
    Cl.CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Gough MR, et al. Equine Vet J, 2002, 34(1), 80-84.
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