Sutezolid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

一种恶唑烷酮抗生素，在体外和体内具有有效的抗结核活性。

An oxazolidinone antibiotic that possesses potent antituberculosis activity in vitro and in vivo; significantly shorten the duration of therapy for drug-susceptible as well as multidrug-resistant tuberculosis.Bacterial Infection Phase 2 Clinical(In Vitro):Sutezolid (PNU-100480) exhibits excellent in vitro activity against multiple clinical isolates of Mycobacterium avium complex (MIC’s=0.5-4 μg/mL).(In Vivo):Sutezolid (PNU-100480) is a thiomorpholinyl analog of linezolid with superior efficacy against M. tuberculosis in the hollow-fiber, mouse, and whole-blood models.

Sutezolid (PNU-100480) exhibits excellent in vitro activity against multiple clinical isolates of Mycobacterium avium complex (MIC’s=0.5-4 μg/mL).

Sutezolid (PNU-100480) is a thiomorpholinyl analog of linezolid with superior efficacy against M. tuberculosis in the hollow-fiber, mouse, and whole-blood models.

PNU-100480 | PNU100480 | PF-02341272 | PF02341272 | U-100480

GPCR/G Protein

Antibacterial

Antibacterial

Infection

Bacterial Infection

168828-58-8

353.4117

C16H20FN3O3S

>98% (HPLC)

10 mM in DMSO

CC(NC[C@H]1CN(C2=CC=C(N3CCSCC3)C(F)=C2)C(O1)=O)=O

Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-

(-20℃)

With Ice Pack

≥ 2 years