ST-4206

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

ST1535 的代谢产物，是有效的选择性 A2A 腺苷受体拮抗剂，Ki 为 6.6 nM。

A metabolite of ST1535, which is potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM.

ST4206 inhibits agonist-induced cAMP accumulation with an IC50 of 990 nM.

ST4206 (10, 20, and 40 mg/kg, p.o.) antagonizes haloperidol-induced catalepsy, and increases motor activity in a dose dependent manner in mice.ST4206 (20 and 40 mg/kg) significantly increases the number of contralateral turns induced by l-DOPA in rats. ST4206 is orally active at concentrations of 10, 20, and 40 mg/kg in haloperidol-induced catalepsy in mice.

ST 4206 | ST4206

Apoptosis

Adenosine Receptor

Adenosine Receptor

——

——

1246018-36-9

286.299

C12H14N8O

>98% (HPLC)

——

CC(CCC1=NC(N)=C2N=C(N3N=CC=N3)N(C)C2=N1)=O

4-(6-amino-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-2-yl)butan-2-one

(-20℃)

With Ice Pack

≥ 2 years