Esomeprazole magnesium salt ( —— )

产品货号. M10711 CAS No. 1198768-91-0

一种质子泵抑制剂，通过抑制壁细胞中的 H+/K+-ATP 酶来减少胃酸分泌。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
25MG	￥9858	有现货
50MG	￥12834	有现货
100MG	￥15750	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

产品询价大包装询价加入购物车

生物学信息

产品名称

Esomeprazole magnesium salt
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

一种质子泵抑制剂，通过抑制壁细胞中的 H+/K+-ATP 酶来减少胃酸分泌。
产品描述

A proton pump inhibitor that reduces stomach acid secretion by inhibition of the H+/K+-ATPase in the parietal cells; the (S)-(?)-enantiomer of omeprazole for treatment of dyspepsia, peptic ulcer disease, and gastroesophageal reflux disease.Ulcer Approved.
体外实验

Esomeprazole (25-100 μM; 20 hours; MDA-MB-468 cells) treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification.Cell Viability Assay Cell Line:MDA-MB-468 cells Concentration:25 μM, 50 μM, 75 μM, 100 μM Incubation Time:20 hours Result:Suppressed growth of triple-negative breast cancer cell in vitro in a dose-dependent manner.
体内实验

Esomeprazole (25-100 μM; 20 hours; MDA-MB-468 cells) treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification.Cell Viability Assay Cell Line:MDA-MB-468 cells Concentration:25 μM, 50 μM, 75 μM, 100 μM Incubation Time:20 hours Result:Suppressed growth of triple-negative breast cancer cell in vitro in a dose-dependent manner.
同义词

——
通路

Membrane Transporter/Ion Channel
靶点

Proton Pump
受体

Proton Pump
研究领域

Other Indications
适应症

Ulcer

化学信息

CAS Number

1198768-91-0
分子量

368.7126
分子式

C17H18MgN3O3S+
纯度

>98% (HPLC)
溶解度

10 mM in DMSO
SMILES

CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC.[Mg]
化学全称

1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, magnesium salt (1:1)