Ceftriaxone sodium ( Ceftriaxone disodium hemiheptahydrate | Ro 13-9904 | Rosihlitazone )

产品货号. M10216 CAS No. 104376-79-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Ceftriaxone sodium
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

头孢曲松钠水合物是一种抗生素，可用于治疗多种细菌感染。
产品描述

Ceftriaxone sodium hydrate is an antibiotic useful for the treatment of a number of bacterial infections; a third-generation cephalosporin.
体外实验

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体内实验

Animal Model:DGL-induced rat modelDosage:200 mg/kg Administration:i.p.Result:Reduced the BUN、Cr 、AST and ALT levels.Attenuated the MDA levels and enhanced GPx and CAT activities.Reduced the levels of IL-1β and TNF-α mRNA.Animal Model:PTZ-induced rat model Dosage:200, 400 mg/kg Administration:i.p. 60 min before to PTZ (70 mg/kg)Result:Both of the two ceftriaxone groups had lower spike percentages than the saline group.Significantly lower MDA levels and higher SOD activity in 200 and 400 mg/kg.
同义词

Ceftriaxone disodium hemiheptahydrate | Ro 13-9904 | Rosihlitazone
通路

Others
靶点

Other Targets
受体

Others
研究领域

Infection
适应症

——

CAS Number

104376-79-6
分子量

662
分子式

C18H16N8Na2O7S3·3·5H2O
纯度

>98% (HPLC)
溶解度

DMSO: 1mg/ml(1.51 mM); Water: 100mg/ml (151.15 mM); Ethanol: <1mg/ml
SMILES

CN1C(=NC(=O)C(=O)N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)[O-].[Na+]
化学全称

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1.Brogden RN, et al. Drugs, 1988, 35(6), 604-645.

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