Edetol

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Quadrol 是一种免疫刺激剂，已被认为是加速伤口愈合的潜在有用活性分子。

A kind of complexing agent, used for chemical copper plating on PCB manufacturing.

Results show that viability of macrophages incubated with Quadrol at concentrations of 0.5 mM, 1 mM and 4mM are identical to that for controls. Viability, however, is reduced to 50% of control at concentrations of 16 mM to 32 mM. After four hours, at concentrations of 1 mM and 4 mM, Quadrol produces enhanced spreading of 88% and 80%, respectively, as compared to the control of 28%. Quadrol, at a concentration of 16 mM, shows reduced percentage of spreading of macrophages after four hours. Exposure of macrophages to 1.0 mM or 4.0 mM Quadrol concentrations enhances phagocytic activity, 41% and 57%, respectively, over that of the cells exposed to media alone (34%).

On day eight after the implantation, the amount of collagen in the implants of normal mice injected with Quadrol exceeds controls by more than 200% (p<0.025). By day 11, the collagen content increases to over 300% higher than controls (p<0.01) and by the end of two weeks after wounding, the time interval typically required for normal and complete wound healing, the collagen accumulated in the implants of the Quadrol-treated mice is about 50% above control (p<0.1). The accumulation of collagen in the implants of Quadrol treated STZ-diabetic mice about 100% above the untreated diabetic control on days 8 to 11. By day 14, the collagen deposition has increased to 200% above the controls (p<0.0 5).

Edetol | NSC 369219 | NSC-369219 | NSC369219

Others

Other Targets

Others

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102-60-3

292.41

C14H32N2O4

>98% (HPLC)

Soluble in Water

CC(O)CN(CC(O)C)CCN(CC(O)C)CC(O)C

1,1',1'',1'''-Ethylenedinitrilotetrapropan-2-ol

(-20℃)

With Ice Pack

≥ 2 years