S0859

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

S0859 是一种 N-氰基磺酰胺化合物，可逆地抑制 NBC 介导的 pH(i) 恢复。

S0859, an N-cyanosulphonamide compound, reversibly inhibit NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM).

Treatment with NBC inhibitor S0859 significantly increased caspase-3 activity and elevated the number of apoptotic EC. S0859 is potentially important for probing the transporter's functional role in heart and other tissues.

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S0859 | S-0859 | S 0859.

Others

Other Targets

NBC

Cardiovascular Disease

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1019331-10-2

530.04

C29H24ClN3O3S

>98% (HPLC)

DMSO: 10 mM

O=C(N(CC1=CC=C(C2=CC=CC=C2S(=O)(NC#N)=O)C=C1)CC3=CC=C(C)C=C3)C4=CC=CC=C4Cl

2-chloro-N-((2'-(N-cyanosulfamoyl)-[1,1'-biphenyl]-4-yl)methyl)-N-(4-methylbenzyl)benzamide

(-20℃)

With Ice Pack

≥ 2 years