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Lucerastat
CAS No. 141206-42-0
Lucerastat ( N-Butyldeoxygalactonojirimycin;ACT-434964;OGT-923 )
产品货号. M11715 CAS No. 141206-42-0
A galactose analogue that is an UDP-glucose ceramide glucosyltransferase (UGCG/GCS) inhibitor (IC50=41.4 uM).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 50MG | ￥8060 | 有现货 |
|
| 100MG | ￥14256 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Lucerastat
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A galactose analogue that is an UDP-glucose ceramide glucosyltransferase (UGCG/GCS) inhibitor (IC50=41.4 uM).
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产品描述A galactose analogue that is an UDP-glucose ceramide glucosyltransferase (UGCG/GCS) inhibitor (IC50=41.4 uM); prevents glucosylceramide biosynthesis both in vitro and in mouse models of lysosome storage disorders, without affecting α-glucosidase I and II or β-glucocerebrosidase (IC50>1 mM); shows potential as substrate reduction therapy for glycolipid storage disorders such as Gaucher disease and Fabry disease.Other Indication Phase 1 Clinical
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同义词N-Butyldeoxygalactonojirimycin;ACT-434964;OGT-923
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Other Indications
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适应症Other Disease
化学信息
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CAS Number141206-42-0
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分子量219.28
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分子式C10H21NO4
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纯度>98% (HPLC)
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溶解度——
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SMILESO[C@H]1[C@@H](CO)N(CCCC)C[C@H](O)[C@H]1O
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化学全称(2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Platt FM, et al. J Biol Chem. 1994 Oct 28;269(43):27108-14.
2. Andersson U, et al. Biochem Pharmacol. 2000 Apr 1;59(7):821-9.
3. Kasperzyk JL, et al. J Neurochem. 2004 May;89(3):645-53.
2. Andersson U, et al. Biochem Pharmacol. 2000 Apr 1;59(7):821-9.
3. Kasperzyk JL, et al. J Neurochem. 2004 May;89(3):645-53.
产品手册
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