
LtaS-IN-1
CAS No. 877950-01-1
LtaS-IN-1 ( —— )
产品货号. M26284 CAS No. 877950-01-1
LtaS-IN-1 是一种有效的脂磷壁酸合成抑制剂,可通过改变细胞壁形态来抑制多重耐药 (MDR) 屎肠球菌的合成。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥988 | 有现货 |
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10MG | ¥1442 | 有现货 |
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25MG | ¥2535 | 有现货 |
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50MG | ¥3953 | 有现货 |
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100MG | ¥5800 | 有现货 |
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200MG | 获取报价 | 有现货 |
![]() ![]() |
500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称LtaS-IN-1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述LtaS-IN-1 是一种有效的脂磷壁酸合成抑制剂,可通过改变细胞壁形态来抑制多重耐药 (MDR) 屎肠球菌的合成。
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产品描述LtaS-IN-1 is an effective inhibitor of Lipoteichoic acid synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 is against Enterococcus spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 inhibits strain E1630 and E1590 with MIC values of 0.5 μg/mL.(In Vitro):LtaS-IN-1 (20 μM) combines with either ampicillin (20 μg/mL), gentamicin (10 μg/mL), linezolid (5 μg/mL), daptomycin (10 μg/mL+50 μg/mL calcium chloride) or vancomycin (20 μg/mL) can inhibit strains E7128 and E7130 growth by 97-100%, while LtaS-IN-1 alone only gives 73% (strain E7128) and 8% (strain E7130) of growth inhibition, respectively. LtaS-IN-1 (0-100 μM) inhibits strain E745 growth as a concentration-dependent manner. LtaS-IN-1 (10 μM) leads to a 60% reduction in the final OD600 for this strain. Meanwhile, LtaS-IN-1 does not affect E. faecium growth in control group.
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体外实验LtaS-IN-1 (0-100 μM) inhibits strain E745 growth as a concentration-dependent manner. At the concentration 10 μM leads to an 60% reduction in the final OD600 for this strain. Meanwhile, LtaS-IN-1 does not affect E. faecium growth in control group. LtaS-IN-1 is against Enterococcus spp 28 strains withvarying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 inhibits strainE1630 andE1590 with the MIC values of 0.5μg/mL. LtaS-IN-1 (20 μM) combines with either ampicillin (20 μg/mL), gentamicin (10 μg/mL), linezolid (5 μg/mL), daptomycin (10 μg/mL+50 μg/mL calcium chloride) or vancomycin (20 μg/mL) can inhibit strains E7128 and E7130 growthby 97-100%, while LtaS-IN-1 alone only gives 73% (strain E7128) and 8% (strain E7130) of growth inhibition, respectively.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体GABA
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研究领域——
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适应症——
化学信息
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CAS Number877950-01-1
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分子量427.416
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分子式C24H17N3O5
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (292.46 mM)
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SMILESO=C(COC(=O)Cc1coc2ccc3ccccc3c12)Nc1nnc(o1)-c1ccccc1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Nakao T, et al. Broflanilide: A meta-diamide insecticide with a novel mode of action. Bioorg Med Chem. 2016 Feb 1;24(3):372-7.
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