Linarin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Linarin (acacetin-7-O-β-d-rutinoside) 对乙酰胆碱酯酶表现出选择性剂量依赖性抑制作用。

Linarin (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.

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Linarin

Others

Other Targets

TNF-α inhibitor

Others-Field

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480-36-4

592.55

C28H32O14

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (421.91 mM)

CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)OC)O)O)O)O)O)O)O

7-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one

(-20℃)

With Ice Pack

≥ 2 years