Linarin ( Linarin )

产品货号. M18609 CAS No. 480-36-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

Linarin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Linarin (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase.
产品描述

Linarin (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.
同义词

Linarin
通路

Others
靶点

Other Targets
受体

TNF-α inhibitor
研究领域

Others-Field
适应症

——

CAS Number

480-36-4
分子量

592.55
分子式

C28H32O14
纯度

98%
溶解度

——
SMILES

CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)OC)O)O)O)O)O)O)O
化学全称

7-((6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one

计算器

产品手册

关联产品

1-Deoxymannojirimyci...

1-Deoxymannojirimycin hydrochloride is a selective α1,2-mannosidase inhibitor(IC50: 20 μM). 1-Deoxymannojirimycin hydrochloride also inhibits HIV‐1 strains and has poor antiviral activity.
Dodecenylsuccinic an...

Dodecenylsuccinic anhydride can be grafted with collagen hydrogels as a hydrophobic wound dressing to incorporate simvastatin.
Methyl nomilinate

Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.