Lenacapavir ( GS-6207 )

产品货号. M26233 CAS No. 2189684-44-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Lenacapavir
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Lenacapavir is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.
产品描述

Lenacapavir is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.(In Vitro):Lenacapavir displays a mean EC50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells. Lenacapavir shows sub-nanomolar potency in target cells with EC50 of 23 pM, in a full-cycle assay with EC50 of 25 pM and in producer cells with EC50 of 439 pM.
同义词

GS-6207
通路

Others
靶点

Other Targets
受体

——
研究领域

——
适应症

——

CAS Number

2189684-44-2
分子量

968.3
分子式

C39H32ClF10N7O5S2
纯度

>98% (HPLC)
溶解度

——
SMILES

[H][C@]12C[C@@]1([H])C(F)(F)c1c2c(nn1CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)c1nc(ccc1-c1ccc(Cl)c2c(NS(C)(=O)=O)nn(CC(F)(F)F)c12)C#CC(C)(C)S(C)(=O)=O)C(F)(F)F
化学全称

——

1.Tagliabue A, Rappuoli R. Vaccine adjuvants:the dream becomes real. Hum Vaccin. 2008 Sep-Oct;4(5):347-9.

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