Latrepirdine ( Latrepirdine dimebolin Dimebon )

产品货号. M17697 CAS No. 97657-92-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Latrepirdine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Latrepirdine is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, GluR, and 5-HT receptors, used as an antihistamine drug.
产品描述

Latrepirdine, also known as dimebolin (sold as Dimebon), is an antihistamine drug which has been used clinically in Russia since 1983. Research is continuing in both Russia and western nations into potential applications as a neuroprotective drug to combat Alzheimer's disease and, possibly, as a nootropic as well. However, a Phase III clinical trial for Alzheimer's disease treatment failed to show any benefit.
同义词

Latrepirdine dimebolin Dimebon
通路

Others
靶点

Other Targets
受体

GluR , Histamine receptor , 5-HT
研究领域

Inflammation/Immunology
适应症

——

CAS Number

97657-92-6
分子量

392.37
分子式

C21H25N3·2HCl
纯度

98%
溶解度

DMSO : 6.4 mg/mL. 16.31 mM;
SMILES

CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C.Cl.Cl
化学全称

2,8-dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride

1. Zhang S, et al. J Alzheimers Dis, 2010, 21(2), 389-402.

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