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Lactisole

CAS No. 150436-68-3

Lactisole ( 2-(4-Methoxyphenoxy)propanoic acid )

产品货号. M28055 CAS No. 150436-68-3

Lactisole is an inhibitor of the glucose-sensing receptor.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥284 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Lactisole
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Lactisole is an inhibitor of the glucose-sensing receptor.
  • 产品描述
    Lactisole is an inhibitor of the glucose-sensing receptor.(In Vitro):In MIN6 cells, in a dose-dependent manner, lactisole inhibited insulin secretion induced by sweeteners, acesulfame-K, sucralose and glycyrrhizin. The IC50 was ~4 mmol/l. Lactisole attenuated the elevation of cytoplasmic Ca2+ concentration ([Ca2+]c) evoked by sucralose and acesulfame-K but did not affect the elevation of intracellular cAMP concentration ([cAMP]c) induced by these sweeteners. Lactisole also inhibited the action of glucose in MIN6 cells. Thus, lactisole significantly reduced elevations of intracellular [NADH] and intracellular [ATP] induced by glucose, and also inhibited glucose-induced insulin secretion.
  • 同义词
    2-(4-Methoxyphenoxy)propanoic acid
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Apoptosis;PKG
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    150436-68-3
  • 分子量
    218.2
  • 分子式
    C10H11NaO4
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    [Na+].COc1ccc(OC(C)C([O-])=O)cc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Singh T, et al. Nitric oxide donor exisulind is an effective inhibitor of murine photocarcinogenesis. Photochem Photobiol. 2012 Sep-Oct;88(5):1141-8.
产品手册
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