LYS228 ( LYS-228;LYS 228 )

产品货号. M12777 CAS No. 1810051-96-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

LYS228
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml.
产品描述

LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml; LYS228 is stable against Metallo-β-lactamases (MBLs), and shows small or no MIC shifts for most SBLs (serine β-lactamases), including CTX-Ms, KPCs and OXA-types.Bacterial Infection Phase 2 Clinical
同义词

LYS-228;LYS 228
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

Infection
适应症

Bacterial Infection

CAS Number

1810051-96-7
分子量

518.47
分子式

C16H18N6O10S2
纯度

>98% (HPLC)
溶解度

——
SMILES

C1CC1(C(=O)O)ON=C(C2=CSC(=N2)N)C(=O)NC3C(N(C3=O)S(=O)(=O)O)CN4CCOC4=O
化学全称

1-((((Z)-1-(2-aminothiazol-4-yl)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-yl)methyl)-1-sulfoazetidin-3-yl)amino)ethylidene)amino)oxy)cyclopropane-1-carboxylic acid

1. Reck F, et al. Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755.

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