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LTX-315
CAS No. 1345407-05-7
LTX-315 ( Oncopore )
产品货号. M11383 CAS No. 1345407-05-7
LTX-315 (Oncopore) 是一种合成的 9 聚体抗癌肽，可优先透化线粒体膜。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥713 | 有现货 |
|
| 5MG | ￥1021 | 有现货 |
|
| 10MG | ￥1742 | 有现货 |
|
| 25MG | ￥3183 | 有现货 |
|
| 50MG | ￥4739 | 有现货 |
|
| 100MG | 获取报价 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称LTX-315
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述LTX-315 (Oncopore) 是一种合成的 9 聚体抗癌肽，可优先透化线粒体膜。
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产品描述LTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes, thereby causing partially BAX/BAK1-regulated, caspase-independent necrosis; triggers immunogenic cell death, induces cell death and DAMP release by mitochondria distortion in human melanoma cells.Breast Cancer Phase 2 Clinical.
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体外实验——
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体内实验——
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同义词Oncopore
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通路Others
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靶点Other Targets
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受体Others
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研究领域Cancer
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适应症Breast Cancer
化学信息
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CAS Number1345407-05-7
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分子量1439.823
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分子式C78H106N18O9
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纯度>98% (HPLC)
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溶解度Ethanol: 100 mg/mL (69.45 mM); DMSO: <1 mg/mL; Water: 100 mg/mL (69.45 mM) （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESNCCCC[C@@H](C(N)=O)NC([C@H](C(C1=CC=CC=C1)C2=CC=CC=C2)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CC5=CNC6=C5C=CC=C6)NC([C@H](CC7=CNC8=C7C=CC=C8)NC([C@H](CCCCN)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O
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化学全称L-Lysyl-L-lysyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-β-phenyl-L-phenylalanyl-L-lysinamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Haug BE, et al. J Med Chem. 2016 Apr 14;59(7):2918-27.
2. Forveille S, et al. Cell Cycle. 2015;14(21):3506-12.
3. Zhou H, et al. Oncotarget. 2015 Sep 29;6(29):26599-614.
4. Eike LM, et al. Oncotarget. 2015 Oct 27;6(33):34910-23.
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