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LTX-315

CAS No. 1345407-05-7

LTX-315 ( Oncopore )

产品货号. M11383 CAS No. 1345407-05-7

LTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥713 有现货
5MG ¥1021 有现货
10MG ¥1742 有现货
25MG ¥3183 有现货
50MG ¥4739 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    LTX-315
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    LTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes.
  • 产品描述
    LTX-315 (Oncopore) is a synthetic 9-mer anticancer peptide that preferentially permeabilizes mitochondrial membranes, thereby causing partially BAX/BAK1-regulated, caspase-independent necrosis; triggers immunogenic cell death, induces cell death and DAMP release by mitochondria distortion in human melanoma cells.Breast Cancer Phase 2 Clinical
  • 同义词
    Oncopore
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Cancer
  • 适应症
    Breast Cancer

化学信息

  • CAS Number
    1345407-05-7
  • 分子量
    1439.82
  • 分子式
    C78H106N18O9
  • 纯度
    >98% (HPLC)
  • 溶解度
    Ethanol: 100 mg/mL (69.45 mM); DMSO: <1 mg/mL; Water: 100 mg/mL (69.45 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    NCCCC[C@@H](C(N)=O)NC([C@H](C(C1=CC=CC=C1)C2=CC=CC=C2)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CC5=CNC6=C5C=CC=C6)NC([C@H](CC7=CNC8=C7C=CC=C8)NC([C@H](CCCCN)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O
  • 化学全称
    L-Lysyl-L-lysyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-β-phenyl-L-phenylalanyl-L-lysinamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Haug BE, et al. J Med Chem. 2016 Apr 14;59(7):2918-27.
2. Forveille S, et al. Cell Cycle. 2015;14(21):3506-12.
3. Zhou H, et al. Oncotarget. 2015 Sep 29;6(29):26599-614.
4. Eike LM, et al. Oncotarget. 2015 Oct 27;6(33):34910-23.
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