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LRE1
CAS No. 1252362-53-0
LRE1 ( —— )
产品货号. M26744 CAS No. 1252362-53-0
LRE1 是一种特异性变构可溶性腺苷酸环化酶抑制剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥446 | 有现货 |
|
| 10MG | ￥786 | 有现货 |
|
| 25MG | ￥1531 | 有现货 |
|
| 50MG | ￥2876 | 有现货 |
|
| 100MG | ￥4285 | 有现货 |
|
| 500MG | ￥9558 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称LRE1
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述LRE1 是一种特异性变构可溶性腺苷酸环化酶抑制剂。
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产品描述LRE1 is a specific and allosteric soluble adenylyl cyclase inhibitor.(In Vitro):LRE1 prevents sAC-dependent processes in cellular and physiological systems and facilitates exploration of the therapeutic potential of sAC inhibition. LRE1 binds to the bicarbonate activator binding site and suppresses soluble adenylyl cyclase (sAC) via a unique allosteric mechanism.
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体外实验Western Blot Analysis Cell Line:Mouse cauda sperm Concentration:0.5-100 μM Incubation Time:60 minutes Result:LRE1 inhibits sAC dependent sperm capacitation.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体S1PR1
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研究领域——
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适应症——
化学信息
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CAS Number1252362-53-0
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分子量280.77
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分子式C12H13ClN4S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (445.19 mM)
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SMILESNc1nc(Cl)cc(n1)N(Cc1cccs1)C1CC1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Bigaud M, et al. Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism. PLoS One. 2016 Dec 22;11(12):e0168252.
产品手册
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