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LQZ-7I
CAS No. 195822-23-2
LQZ-7I ( —— )
产品货号. M22010 CAS No. 195822-23-2
LQZ-7I 是一种存活靶向抑制剂。它口服可有效抑制异种移植肿瘤的生长并诱导肿瘤中生存素的丧失。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥381 | 有现货 |
|
| 10MG | ￥648 | 有现货 |
|
| 25MG | ￥1320 | 有现货 |
|
| 50MG | ￥2130 | 有现货 |
|
| 100MG | ￥3345 | 有现货 |
|
| 500MG | ￥7638 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称LQZ-7I
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述LQZ-7I 是一种存活靶向抑制剂。它口服可有效抑制异种移植肿瘤的生长并诱导肿瘤中生存素的丧失。
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产品描述LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors.
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体外实验Western Blot Analysis Cell Line:PC-3 or C4-2 cells Concentration:10 μM Incubation Time:0-6 hours Result:Reduced the expression of survivin.
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体内实验Animal Model:6-week old male NSG mice Dosage:100 mg/kg; 200 μL vehicle (90% corn oil/10% DMSO) Administration:Oral gavage every other day for a total of ten treatments Result:Significantly suppressed tumor growth without any notable adverse effect on the mice as indicated by lacking changes in body weight and in wet weight of major organs at the end of the study.
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同义词——
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通路Others
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靶点Other Targets
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受体Survivin
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研究领域——
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适应症——
化学信息
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CAS Number195822-23-2
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分子量348.35
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分子式C20H14F2N4
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纯度>98% (HPLC)
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溶解度DMSO:120mg/ml (344.48 Mm; Need ultrasonic)
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SMILESFC1=CC=C(NC2=NC3=CC=CC=C3N=C2NC2=CC=C(F)C=C2)C=C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Robert Peery,et al. Synthesis and Identification of a Novel Lead Targeting Survivin Dimerization for Proteasome-Dependent Degradation. J Med Chem. 2020 Jun 9.
产品手册
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