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LN-1-255
CAS No. 247115-03-3
LN-1-255 ( LN 1-255;LN1255 )
产品货号. M13722 CAS No. 247115-03-3
LN-1-255 is a 6-alkylidene-2'-substituted penicillin sulfone that acts as an effective beta-lactamase inhibitor.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称LN-1-255
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述LN-1-255 is a 6-alkylidene-2'-substituted penicillin sulfone that acts as an effective beta-lactamase inhibitor.
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产品描述LN-1-255 is a 6-alkylidene-2'-substituted penicillin sulfone that acts as an effective beta-lactamase inhibitor; inhibits SHV-1 and SHV-2 beta-lactamases with Ki of 110 nM and 100 nM, significantly enhances the activity of ceftazidime and cefpirome against extended-spectrum cephalosporin and Sme-1 containing carbapenem-resistant clinical strains; also inhibits the class D carbapenemase OXA-48 with IC50 of 3 nM, an important emerging mechanism of antibiotic resistance.
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同义词LN 1-255;LN1255
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域——
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适应症——
化学信息
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CAS Number247115-03-3
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分子量510.45
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分子式C22H19N2NaO9S
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-[[[(3,4-dihydroxyphenyl)acetyl]oxy]methyl]-3-methyl-7-oxo-6-(2-pyridinylmethylene)-, 4,4-dioxide, monosodium salt, (2S,3R,5R,6Z)- (9CI)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Pattanaik P, et al. J Biol Chem. 2009 Jan 9;284(2):945-53.
2. Vallejo JA, et al. J Antimicrob Chemother. 2016 Aug;71(8):2171-80.
3. Vázquez-Ucha JC, et al. Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01172-17.
2. Vallejo JA, et al. J Antimicrob Chemother. 2016 Aug;71(8):2171-80.
3. Vázquez-Ucha JC, et al. Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e01172-17.
产品手册
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