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LM10

CAS No. 1316695-35-8

LM10 ( LM10; LM 10; LM-10 )

产品货号. M17944 CAS No. 1316695-35-8

Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively).

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥243 有现货
10MG ¥381 有现货
25MG ¥786 有现货
50MG ¥1401 有现货
100MG ¥2714 有现货
200MG ¥4269 有现货
500MG ¥6820 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    LM10
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Selective tryptophan 2, 3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively).
  • 产品描述
    LM10 is a selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). LM10 exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. LM10 reduces growth of TDO-expressing P815 mastocytoma tumors in mice.
  • 同义词
    LM10; LM 10; LM-10
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    TDO
  • 研究领域
    Others-Field
  • 适应症
    ——

化学信息

  • CAS Number
    1316695-35-8
  • 分子量
    229.22
  • 分子式
    C11H8FN5
  • 纯度
    98%
  • 溶解度
    ——
  • SMILES
    Fc2cc3ncc(/C=C/c1nnnn1)c3cc2
  • 化学全称
    6-fluoro-3-[(E)-2-(1H-1,2,3,4-tetrazol-5-yl)ethenyl]-1H-indole

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Pilotte L,etal.Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase.Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2497-502.
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