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LDC7559

CAS No. 2407782-01-6

LDC7559 ( —— )

产品货号. M26276 CAS No. 2407782-01-6

LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1596 有现货
10MG ¥2657 有现货
25MG ¥4520 有现货
50MG ¥6383 有现货
100MG ¥9072 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    LDC7559
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.
  • 产品描述
    LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.(In Vitro):LDC7559 (1 and 5 μM) inhibits IL-1β release upon inflammasome activation, and significantly blocks the lethal effect of both human and murine GSDMD NT domains transfected into HEK293T cells.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    VHL
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2407782-01-6
  • 分子量
    349.4
  • 分子式
    C20H19N3O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    O=C(NC1=CC=C2C(OCC3=CC(=NN3C2)C=4C=CC=CC4OC)=C1)C
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.
产品手册
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