L755507

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

L755507 是一种有效的选择性 β3-AR 激动剂 (IC50=35 nM)。

L-755507 is a potent β3-adrenergic receptor partial agonist > 1000-fold selective over β1- and β2-adrenoceptors (EC50 values are 0.43, 580 and > 10000 nM for activation of cloned human β3-, β1- and β2-adrenoceptors respectively). L-755507 stimulates lipolysis in rhesus adipocytes in vitro (EC50 = 3.9 nM).

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L-755507 | L 755507 | L755507

Tyrosine Kinase

Bcr-Abl

β1-adrenergic receptor| β2-adrenergic receptor| β2-adrenergic receptor

Others-Field

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159182-43-1

584.73

C30H40N4O6S

>98% (HPLC)

DMSO : 125 mg/mL. 213.77 mM;

CCCCCCNC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1ccc(CCNC[C@H](O)COc2ccc(O)cc2)cc1

1-hexyl-3-[4-[[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]sulfamoyl]phenyl]urea

(-20℃)

With Ice Pack

≥ 2 years